winn - White Noise Normalization for Mass Spectrometry Profiling Data
Provides a decision-guided workflow for correcting
technical variability in chemical profiling data. Tests for
white noise identify measured features that need correction
while preserving those that already pass. The workflow combines
robust outlier adjustment, adaptive drift detection,
change-point segmentation, batch correction, and probabilistic
quotient normalization in a single pipeline or as modular
steps. It supports parameter tuning using pooled
quality-control samples as well as operation for studies
without pooled controls.